Converging neurobiological and immune pathways in ME/CFS and PAIS

Converging neurobiological and immune pathways in ME/CFS and PAIS

Background

About the study

ME and CFS, or ME/CFS, and post-acute infectious syndromes (PAIS) are similar on clinical and biological levels. Patients from both groups suffer crippling symptoms and we still don’t have a good and reliable way to diagnose or treat them. It is now time for researchers in these different disease areas to join forces and work together for a common goal.

Within the NMCB, combined with existing large PAIS cohorts, the researchers will investigate how ME/CFS and PAIS are developed, especially related to inflammation, the immune system, metabolism, and hormones. Once this foundation is established, they will explore and test promising leads that will improve diagnosis (e.g., biomarkers) and treatments (e.g., trying existing therapies).

Subproject

Team

Kees (C.C.) van den Wijngaard

Senior researcher, RIVM Centre for Infectious Disease Control

Dr. Julia van Heck

Postdoc

Prof. dr. Joppe WR Hovius

Internist infectious diseases consultant Amsterdam UMC

Dr. Ruud P.H. Raijmakers

Principal investigator