The Role of Proteins in Inflammation and Symptoms in ME/CFS

The Role of Proteins in Inflammation and Symptoms in ME/CFS

Background

About the study

Bioactive Peptides in ME/CFS: The Link Between Inflammation and Neurological Abnormalities

This project investigates how bioactive peptides and the enzyme neprilysin (CD10) are involved in ME/CFS. These substances may play a role in inflammation and could potentially serve as measurable biomarkers of the disease.

Aim and Approach
The aim is to better understand the role of bioactive peptides in ME/CFS symptoms. Using innovative Point-of-Care (PoC) technology, blood measurements can be carried out in patients’ homes. This is unique worldwide and makes it possible for people with severe ME/CFS to participate in research.
Using a mobile laboratory, researchers will analyse blood samples for inflammatory markers and bioactive peptides, while also monitoring heart rate and physical activity. They will also examine the enzyme neprilysin in immune cells, which helps break down bioactive peptides.

Verwachte resultaten
Het onderzoek moet nieuwe biologische markers opleveren die kunnen helpen bij het herkennen en begrijpen van ME/CVS.

Subproject

Team

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